Maternal antibodies reduce costs of an immune response during development

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Maternal antibodies reduce costs of an immune response during development.

Young vertebrates are dependent primarily on innate immunity and maternally derived antibodies for immune defense. This reliance on innate immunity and the associated inflammatory response often leads to reduced growth rates after antigenic challenge. However, if offspring have maternal antibodies that recognize an antigen, these antibodies should block stimulation of the inflammatory response ...

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ژورنال

عنوان ژورنال: Journal of Experimental Biology

سال: 2008

ISSN: 1477-9145,0022-0949

DOI: 10.1242/jeb.012344